个人简介
汪高博，中共党员，工学博士，硕士研究生导师。主要研究方向为微流控生物传感器、经皮药物递送系统及植入式诊疗器件的开发。近年来，在Materials Today Bio, Advanced Science, Science Advances, Advanced Healthcare Materials, Analytical Chemistry等国际期刊共发表SCI论文18篇。担任Biomedical Engineering Communications, VIEW等期刊青年编委。
联系方式
地址：河南医药大学北区科技楼生物医学工程系办公室717
电话：13683934173
E-mail: wanggaobo@xxmu.edu.cn
研究方向
微流控检测芯片；微针经皮给药；植入式诊疗器件
招生方向
专业型硕士：电子信息
教育背景
2018/12-2022/12, 香港城市大学, 生物医学工程，博士
2016/09-2018/08, 韩国高丽大学, 生物融合工程，硕士
2012/09-2016/06, 河南科技学院, 化学工程与工艺，学士
工作经历
2024/09-至今, 河南医药大学，医学工程学院，讲师
2023/03-2024/08, 日本东北大学, 精密机械系, 博士后
2018/09-2018/11, 香港城市大学，生物医学工程系，助理研究员
承担项目
1. 国家自然科学基金委，青年科学基金项目（C类），基于仿生门控与级联效应的局部给药系统构建及肿瘤治疗研究，30万，2026.01-2028.12，主持；
2. 河南医药大学博士科研启动项目，便携式微纳生物传感器，80万，2024.10-2027.12，主持；
3. 日本学术振兴会（科学研究费助成金S），基于离子传输的电子皮肤，22H04956，960万，2022.04-2027.03，参与；
4. 深圳市科技创新局，基于微流控磁粒子的前列腺癌视觉量化检测微芯片的研究，JCYJ20210324134006017，40万，2021.10 – 2024.10，参与；
近五年代表性论文(#:共同作者/equal contribution; *:通讯作者/corresponding author)
1. Gaobo Wang, Natsuho Moriyama, Soichiro Tottori, Matsuhiko Nishizawa*. Recent advances in iontophoresis-assisted microneedle devices for transdermal biosensing and drug delivery. Materials Today Bio 31, 101504, 2025
2. Gaobo Wang, Yuina Abe, Soichiro Tottori, Shuto Osaki, Matsuhiko Nishizawa*. Porous Microneedles: Transdermal Salt Bridge for Biomedical Device Engineering. Current Opinion in Biomedical Engineering 100593, 2025
3. Gaobo Wang, Chenxing Li, Yunhao Sun, Soichiro Tottori, Matsuhiko Nishizawa*. Tunable electroosmotic pumping via electrical double layer charging. ACS Materials Letters 7, 3, 741-745, 2025
4. Gaobo Wang#, Yuyue Zhang#, Hoi Kwan Kwong#, Mengjia Zheng, Jianpeng Wu, Chenyu Cui, Kannie W. Y. Chan, Chenjie Xu*, and Ting-Hsuan Chen*. On-site melanoma diagnosis utilizing a swellable microneedle-assisted skin interstitial fluid sampling and a microfluidic particle dam for visual quantification of S100A1. Advanced Science 2306188, 2024
5. Gaobo Wang, Kosuke Kato, Sae Ichinose, Daisuke Inoue, Airi Kobayashi, Hitoshi Terui, Soichiro Tottori, Makoto Kanzaki, Matsuhiko Nishizawa*. Bilaterally aligned electroosmotic flow generated by porous microneedle device for dual-mode delivery. Advanced Healthcare Materials 2401181, 2024
6. Gaobo Wang, Kosuke Kato, Izuru Aoki, Sae Ichinose, Daisuke Inoue, Soichiro Tottori and Matsuhiko Nishizawa*. Transdermal drug delivery using a porous microneedle device driven by a hydrogel electroosmotic pump. Journal of Materials Chemistry B 12, 1490-1494, 2024
7. Gaobo Wang#, Jiaheng Li#, Siying Wu, Tianyi Jiang, and Ting-Hsuan Chen*. A fully integrated, ready-to-use distance-based chemosensor for visual quantification of multiple heavy metal ions. Analytical Chemistry 94, 46, 15925–15929, 2022
8. Gaobo Wang, Minghui Wu, Lok Ting Chu, Ting-Hsuan Chen*. Portable microfluidic device with thermometer-like display for real-time visual quantitation of Cadmium(ii) contamination in drinking water. Analytica Chimica Acta 1160, 338444. 2022
9. Gaobo Wang#, Lok Ting Chu#, Hogi Hartanto, William Budi Utomo, Reynard Aaron Pravasta, and Ting-Hsuan Chen*. Microfluidic particle dam for visual and quantitative detection of lead ions. ACS Sensors 5, 19–23, 2020
10. Minghui Wu#, Gaobo Wang#, Lok Ting Chu, Hanjin Huang, Ting-Hsuan Chen*. Cascade-amplified microfluidic particle accumulation enabling quantification of lead ions through visual inspection. Sensors and Actuators B: Chemical 324, 128727, 2020
11. Hamidreza Shirinkami#, Gaobo Wang#, Jinhyeok Park, Joonhyang Ahn, Yeonho Choi*, Honggu Chun*. Red blood cell and white blood cell separation using a lateral-dimension scalable microchip based on hydraulic jump and sedimentation. Sensors and Actuators B: Chemical 307, 127412, 2020
12. Minghui Wu#, Siying Wu#, Gaobo Wang, Wengang Liu, Lok Ting Chu, Tianyi Jiang, Hoi Kwan Kwong, Hiu Lam Chow, Iris Wai Sum Li, Ting-Hsuan Chen*. Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees. Science Advances 8(22), eabn6064, 2021
13. Daigo Terutsuki, Sho Miyazawa, Junya Takagi, Akihiro Yamada, Yunhao Sun, Hiroya Abe, Gaobo Wang, Matsuhiko Nishizawa*. Spatiotemporally controllable chemical delivery utilizing electroosmosis flow generated in combination of anionic and cationic hydrogel. Advanced Functional Materials 34, 2304946, 2024
14. Jiaheng Li, Lok Ting Chu, Hogi Hartanto, Guihuan Guo, Lu Liu, Jianpeng Wu, Minghui Wu, Chenyu Cui, Gaobo Wang, Wengang Liu, Hoi Kwan Kwong, Siying Wu, Ting-Hsuan Chen*. Microfluidic particle counter visualizing mucosal antibodies against SARS-CoV-2 in the upper respiratory tract for rapid evaluation of immune protection. Lab Chip 24, 2658-2668, 2024
15. Minghui Wu, Hogi Hartanto, Siying Wu, Tianyi Jiang, Gaobo Wang, Ting-Hsuan Chen*. Visualizing alpha-fetoprotein level in undiluted serum based on microfluidic particle accumulation. Sensors and Actuators B: Chemical 390, 133963. 2023
16. Tianyi Jiang, Gaobo Wang and Ting-Hsuan Chen*. Microfluidic particle accumulation for visual quantitation of copper ions. Microchimica Acta 188, 176, 2021
17. Siying Wu, Minghui Wu, Gaobo Wang, Ting-Hsuan Chen*. Visual quantitation of silver contamination in fresh water via accumulative length of microparticles in capillary-driven microfluidic devices. Talanta 235, 122707, 2021
18. Soichiro Tottori, Sae Ichinose, Fumika Sakai, Reiji Segawa, Taiki Yokoyama, Gaobo Wang and Matsuhiko Nishizawa*. Quantitative evaluation of accelerated transdermal drug delivery by electroosmosis via frustoconical porous microneedles. Journal of Materials Chemistry B 13, 5023-5026, 2025
会议报告
1. Gaobo Wang, Hamidreza Shirinkami, Honggu Chun*. Leukocyte and Erythrocyte Sorting Microchip Using Hydraulic Jump Phenomenon. The Korean Biochip Society, Pyeongchang, South Korea, 16-18 May (2018)
2. Gaobo Wang, Lok Ting Chu, Hogi Hartanto, William Budi Utomo, Reynard Aaron Pravasta, and Ting-Hsuan Chen*. Microfluidic Particle Dam for Visual and Quantitative Detection of Lead Ions. The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Congress Center Basel, Basel, Switzerland, 27-31 October (2019)
3. Gaobo Wang, Yuyue Zhang, Hoi Kwan Kwong, Mengjia Zheng, Jianpeng Wu, Chenyu Cui, Kannie W. Y. Chan, Chenjie Xu*, and Ting-Hsuan Chen*. On-site melanoma diagnosis utilizing a swellable microneedle-assisted skin interstitial fluid sampling and a microfluidic particle dam for visual quantification of S100A1. CHEMINAS48, Kumamoto, Japan, 6-8 November (2023)
4. 汪高博. 基于多孔微针的经皮药物递送系统研究（口头报告）, “微系统与纳米工程（MINE）”学术年会，中国西安，Sep 21-23, 2024
5. 汪高博. Microneedle for Localized Drug Delivery（Poster）, 第十届上海国际分析化学研讨会，中国上海，Nov 18-19, 2024
6. 汪高博. 电渗流辅助下的智能可控局部给药器件研究（口头报告）, 中国微米纳米技术学会第十届青年科学家论坛，中国南京，May, 16-18 2025
7. 汪高博. 微纳生物医学器件在精准诊断与治疗中的应用（口头报告）, 2025先进功能材料与器件学术研讨会，中国西安，June 27-29, 2025
8. 汪高博. 基于距离读数的微流控诊断平台（口头报告），中国微米纳米技术学会第八届微流控技术应用创新论坛，中国广州，Aug 1-4, 2025
